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| Title | : | The Mechanism of Neuregulin (NRG)1/ErbB Signaling in Spermatogonial Proliferation of Japanese Red-Bellied Newt (Cynops pyrrhogaster) Testis |
| Authors | : | Oral, Ozlem |
| Issue Date | : | 25-Sep-2008 |
| Abstract | : | Spermatogenesis is a complex process, consisting of highly organized steps controlled by co-action of hormones, such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and testicular somatic cells. ln newt testis, FSH stimulates spermatogonial proliferation
and differentiation into primary spermatocytes through the receptor expressed on its target somatic cells, namely Sertoli cells. Though it is considered that the FSH effects are necessary to be mediated by local paracrine factors, which are secreted from Sertoli cells and act directly on
spermatogonia within the testis, such factofs have not been identified yet. This dissertation aimed to identify FSH-upregulated local factors and their signaling mechanism exerted directly in
spermatogonial proliferation in newt (Cynops pyrrhogaster) testis. |
| Type Local | : | 博士論文 |
| Publisher | : | 熊本大学 |
| URI | : | http://hdl.handle.net/2298/11152 |
| Appears in Collections | : | Thesis or Dissertation
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Please use this identifier to cite or link to this item:
http://hdl.handle.net/2298/11152
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