HOME   Japanese    

Kumamoto University Repository System >
Pharmacy >
Journal Article (Pharmacy) >

 

Files in This Item:

File Description SizeFormat
T_66_39_7726-7731.pdf193KbAdobe PDFView/Open
Title :Enantioselective alkynylation of carbonyl compounds with trimethoxysilylalkynes catalyzed by lithium binaphtholate
Authors :Ueda, Tomohiro
Tanaka, Kana
Ichibakase, Tomonori
Orito, Yuya
Nakajima, Makoto
Issue Date :25-Sep-2010
Citation jtitle :Tetrahedron
vol. :66
no. :39
start page :7726
end page :7731
Abstract :Enantioselective alkynylation of aldehydes and ketones was accomplished using trimethoxysilylalkynes as alkynylating reagents and lithium 3,3′-diphenylbinaphtholate as a catalyst. Optically active propargylic alcohols were obtained in good to high chemical yields and enantioselectivities. Alkynylation of acetylpyridines afforded biologically active pyridyl propargylic alcohols in good enantioselectivities.
URL :http://www.sciencedirect.com/science/article/pii/S0040402010011555
Type Local :雑誌掲載論文
Publisher :Elsevier
Rights :© 2010 Elsevier Ltd
URI :http://hdl.handle.net/2298/19479
Appears in Collections:Journal Article (Pharmacy)
Please use this identifier to cite or link to this item: http://hdl.handle.net/2298/19479