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Title :Study on Tomato-Saponin and Onion Sulfide : Biotechnological Production of Natural Products
Authors :El-Aasr, Mona Abdel-Hamid Mohamed
Issue Date :25-Sep-2010
Abstract :I have been interested in vegetables which are expected to have many biological activities. Among them, I have focused on the sciences of tomato (Solanum lycopersicum L.) and onion (Allium cepa L.).Regarding to tomato, We have developed a tomato-health food with co-operation of a company (N.D.R.Co., Ltd.) and are trying to apply for persons suffering from high blood pressure, high blood sugar level, and atopic dermatitis to accumulate the data for future use.Meanwhile, onion is a rich source of organosulfur compounds, which are mainly responsible for many biological activities.We have found that onionin A significantly inhibited CD163 expression;this finding suggests that onionin A has a potential to suppress tumor cell proliferation by inhibition of M2 macrophage polarization.For exhibiting maximum biological activities from tomato, tomato should be used as a fresh juice homogenized with water or freeze-dried.On the other hand, onion should be taken in raw (uncooked) since onion contains beneficial sulfur compounds which are destroyed by cooking.
Type Local :博士論文
Publisher :熊本大学
Comment :熊本大学大学院薬学教育部 分子機能薬学専攻
URI :http://hdl.handle.net/2298/22162
Appears in Collections:Doctor of Pharmacy
Please use this identifier to cite or link to this item: http://hdl.handle.net/2298/22162